New article from University of Modena and Reggio Emilia, Modena, Italy, Anti-TNF-α Drugs Differently Affect the TNFα-sTNFR System and Monocyte Subsets in Patients with Psoriasis.PLoS ONE, 2016.

      Gibellini L, De Biasi S, Bianchini E, et al. Anti-TNF-α Drugs Differently Affect the TNFα-sTNFR System and Monocyte Subsets in Patients with Psoriasis. Richard Y, ed. PLoS ONE. 11(12), 2016.
     
     Drug and Anti-Drug Levels of Infliximab, Adalimumab and Etanercept are Measured by SHIKARI® ELISA Kits From Matriks Biotek®

The study suggests that a complex remodelling of the TNF-α/sTNFR system occurs in patients with psoriasis treated with anti-TNF-α drugs. Other studies are, however, needed to further characterize functional changes of monocytes in patients treated with different drugs, and that could devote their attention to other early, crucial aspects of inflammatory phenomena modulated by these drugs. Therefore, the correlations between plasma levels of TNF-α, its soluble receptor, the phenotype of monocytes and their ability to produce cytokines must be investigated also in other human diseases that benefit of he treatment with molecules that block TNF-α.

For fulltext article:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147951/pdf/pone.0167757.pdf 

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